2-Imidazolidinone, 1-(2-hydroxyethyl)-


Chemical Name: 2-Imidazolidinone, 1-(2-hydroxyethyl)-
CAS Number: 3699-54-5
Product Number: AG003CUT(AGN-PC-03W5TJ)
Synonyms:
MDL No:
Molecular Formula: C5H10N2O2
Molecular Weight: 130.1451

Identification/Properties


Properties
MP:
46-49°C
BP:
400.1 °C at 760 mmHg
Storage:
Keep in dry area;Room Temperature;
Form:
Solid
Stability:
Hygroscopic
Refractive Index:
n20/D 1.466
Computed Properties
Molecular Weight:
130.147g/mol
XLogP3:
-1.4
Hydrogen Bond Donor Count:
2
Hydrogen Bond Acceptor Count:
2
Rotatable Bond Count:
2
Exact Mass:
130.074g/mol
Monoisotopic Mass:
130.074g/mol
Topological Polar Surface Area:
52.6A^2
Heavy Atom Count:
9
Formal Charge:
0
Complexity:
116
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information


GHS Pictogram:
Signal Word:
Warning
UN#:
N/A
Hazard Statements:
H317-H319
Precautionary Statements:
P280-P305+P351+P338
Class:
N/A
Packing Group:
N/A

NMR Spectrum


Other Analytical Data


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Chemical Structure



1-(2-Hydroxyethyl)imidazolidin-2-one, also known as HEI, is a versatile compound widely used in chemical synthesis processes. Its primary application lies in its role as a highly efficient and selective chiral auxiliary in asymmetric synthesis. HEI can effectively catalyze a variety of chemical reactions, including Diels-Alder cycloadditions, aldol reactions, and Michael additions, by facilitating the formation of enantiomerically pure products.In asymmetric synthesis, HEI acts as a chiral source that enables the conversion of prochiral substrates into single enantiomeric forms, enhancing the stereochemical purity of the final compounds. This compound's unique structure and reactivity make it a valuable tool for synthesizing complex molecules with high levels of stereocontrol, making it particularly useful in pharmaceutical and agrochemical industries where enantiomerically pure compounds are crucial.Additionally, 1-(2-Hydroxyethyl)imidazolidin-2-one has shown promising results in the synthesis of biologically active molecules and natural products, further highlighting its significance in the field of organic chemistry. Its ability to facilitate the creation of optically pure compounds with high efficiency and selectivity makes it a valuable asset for chemists seeking to access a wide range of structurally diverse and biologically relevant molecules.