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Brc1cnc(nc1)C
Pyrimidine, 5-bromo-2-methyl-
CCCP1(=O)OP(=O)(CCC)OP(=O)(O1)CCC
1,3,5,2,4,6-Trioxatriphosphorinane, 2,4,6-tripropyl-, 2,4,6-trioxide
CC1(C)OB(OC1(C)C)B1OC(C(O1)(C)C)(C)C
2,2'-Bi-1,3,2-dioxaborolane, 4,4,4',4',5,5,5',5'-octamethyl-
O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.[Pd].[Pd]
Tris(dibenzylideneacetone)dipalladium
C1CCC(CC1)P(C1CCCCC1)C1CCCCC1.Cc1cc(C)c(c(c1)C)N1CCN(C1=[Ru](=Cc1ccccc1)(Cl)Cl)c1c(C)cc(cc1C)C
Ruthenium,[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)-, (SP-5-41)-

Quinoline, 8-methyl-5-(trifluoromethyl)-

Cc1ccc(c2c1nccc2)C(F)(F)F Request for Quotation
Chemical Name: Quinoline, 8-methyl-5-(trifluoromethyl)-
CAS Number: 868668-58-0
Product Number: AG003NIR(AGN-PC-00DK5R)
Synonyms:
MDL No:
Molecular Formula: C11H8F3N
Molecular Weight: 211.1831

Identification/Properties

Properties
BP:
264.5±35.0°C at 760 mmHg
Storage:
Keep in dry area;Room Temperature;
Computed Properties
Molecular Weight:
211.187g/mol
XLogP3:
3.4
Hydrogen Bond Donor Count:
0
Hydrogen Bond Acceptor Count:
4
Rotatable Bond Count:
0
Exact Mass:
211.061g/mol
Monoisotopic Mass:
211.061g/mol
Topological Polar Surface Area:
12.9A^2
Heavy Atom Count:
15
Formal Charge:
0
Complexity:
226
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information

GHS Pictogram:
Signal Word:
Warning
UN#:
-
Hazard Statements:
H302-H315-H319
Precautionary Statements:
P261-P305+P351+P338
Class:
-
Packing Group:
-

NMR Spectrum

Other Analytical Data

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Chemical Structure


8-Methyl-5-(trifluoromethyl)quinoline, also known as $name$, is a valuable compound in chemical synthesis due to its unique properties and versatile applications. This compound serves as a key building block in the creation of various pharmaceuticals, agrochemicals, and advanced materials.In chemical synthesis, $name$ plays a crucial role as a synthetic intermediate in the preparation of biologically active compounds. Its trifluoromethyl group imparts increased lipophilicity and metabolic stability to the final products, enhancing their pharmacological properties. Additionally, the methyl substitution at the 8th position of the quinoline ring provides structural diversity and modulation of biological activity in the synthesized molecules.Furthermore, the presence of the trifluoromethyl group in $name$ offers opportunities for introducing fluorine-containing motifs into target molecules, enabling medicinal chemists to optimize drug efficacy, enhance bioavailability, and improve metabolic profiles. This compound is particularly valuable in the design and synthesis of drug candidates, where the trifluoromethyl group can act as a bioisostere to enhance drug-target interactions and physicochemical properties.Overall, the strategic use of 8-Methyl-5-(trifluoromethyl)quinoline in chemical synthesis enables the efficient construction of diverse molecular scaffolds with enhanced biological activities, making it a valuable tool for the development of novel therapeutics and functional materials.