Imidazo[1,2-a]pyridine-8-carboxylic acid


Chemical Name: Imidazo[1,2-a]pyridine-8-carboxylic acid
CAS Number: 133427-08-4
Product Number: AG0080HO(AGN-PC-00EOUI)
Synonyms:
MDL No:
Molecular Formula: C8H6N2O2
Molecular Weight: 162.1454

Identification/Properties


Computed Properties
Molecular Weight:
162.148g/mol
XLogP3:
1.3
Hydrogen Bond Donor Count:
1
Hydrogen Bond Acceptor Count:
3
Rotatable Bond Count:
1
Exact Mass:
162.043g/mol
Monoisotopic Mass:
162.043g/mol
Topological Polar Surface Area:
54.6A^2
Heavy Atom Count:
12
Formal Charge:
0
Complexity:
196
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

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Chemical Structure



Imidazo[1,2-a]pyridine-8-carboxylic acid serves as a valuable building block in chemical synthesis due to its versatile reactivity and structural properties. This compound is commonly utilized in the development of pharmaceuticals, agrochemicals, and materials science. In organic synthesis, Imidazo[1,2-a]pyridine-8-carboxylic acid can undergo various transformations such as condensation reactions, functional group manipulations, and cross-coupling reactions to generate complex molecules with diverse functionalities. Its heterocyclic nature and unique ring system make it a crucial intermediate in the synthesis of biologically active compounds and molecular probes. Additionally, Imidazo[1,2-a]pyridine-8-carboxylic acid can be used as a ligand in coordination chemistry to form coordination complexes with transition metals, allowing for the exploration of new catalytic processes and material properties.