2-[4-[3-(quinolin-6-ylmethyl)triazolo[4,5-b]pyrazin-5-yl]pyrazol-1-yl]ethanol


Chemical Name: 2-[4-[3-(quinolin-6-ylmethyl)triazolo[4,5-b]pyrazin-5-yl]pyrazol-1-yl]ethanol
CAS Number: 956905-27-4
Product Number: AG01CP5X(AGN-PC-01LTWA)
Synonyms:
MDL No: MFCD12407410
Molecular Formula: C19H16N8O
Molecular Weight: 372.3833

Identification/Properties


Computed Properties
Molecular Weight:
372.392g/mol
XLogP3:
0.7
Hydrogen Bond Donor Count:
1
Hydrogen Bond Acceptor Count:
7
Rotatable Bond Count:
5
Exact Mass:
372.145g/mol
Monoisotopic Mass:
372.145g/mol
Topological Polar Surface Area:
107A^2
Heavy Atom Count:
28
Formal Charge:
0
Complexity:
524
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

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Chemical Structure



PF-04217903 is a potent and selective inhibitor of the kinases c-Met and Ron. In the realm of chemical synthesis, this compound plays a crucial role in the development of targeted therapies for various types of cancer. By specifically targeting and inhibiting the c-Met and Ron kinases, PF-04217903 can effectively interfere with the signaling pathways involved in promoting cancer cell growth and proliferation. This inhibition ultimately leads to the potential suppression of tumor activity and progression. As a key component in the field of medicinal chemistry, PF-04217903 offers a valuable tool for researchers and pharmaceutical companies alike in their efforts to design and create innovative anticancer drugs with improved efficacy and reduced side effects.