2-[4-(methoxymethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane


Chemical Name: 2-[4-(methoxymethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS Number: 936250-15-6
Product Number: AG00GV07(AGN-PC-01NOTD)
Synonyms:
MDL No: MFCD08690234
Molecular Formula: C14H21BO4
Molecular Weight: 264.12514

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The compound 2-[4-(Methoxymethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, commonly known as $name$, is a versatile reagent used in various chemical synthesis reactions. This boronic ester derivative is prized for its ability to participate in a wide range of cross-coupling reactions, particularly in Suzuki-Miyaura coupling. One of the key applications of $name$ in chemical synthesis is in the formation of carbon-carbon bonds. By reacting with aryl halides or pseudohalides in the presence of a palladium catalyst, $name$ facilitates the coupling process to form biaryl compounds. This reaction is highly valuable in the pharmaceutical industry for the synthesis of complex organic molecules and drug candidates.Moreover, $name$ is recognized for its stability and compatibility with a variety of functional groups, making it a preferred choice for building molecular complexity through bond formation. Its tetramethyl substitution offers enhanced steric hindrance, which can influence regioselectivity and improve yield in cross-coupling reactions.In summary, the use of 2-[4-(Methoxymethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane ($name$) in chemical synthesis plays a crucial role in constructing carbon-carbon bonds efficiently and selectively, making it an indispensable tool for organic chemists in the development of new molecules and pharmaceuticals.