2-chloro-3,6-bis(trifluoromethyl)pyridine


Chemical Name: 2-chloro-3,6-bis(trifluoromethyl)pyridine
CAS Number: 175136-26-2
Product Number: AG002097(AGN-PC-02W3B7)
Synonyms:
MDL No:
Molecular Formula: C7H2ClF6N
Molecular Weight: 249.5409

Identification/Properties


Computed Properties
Molecular Weight:
249.54g/mol
XLogP3:
3.6
Hydrogen Bond Donor Count:
0
Hydrogen Bond Acceptor Count:
7
Rotatable Bond Count:
0
Exact Mass:
248.978g/mol
Monoisotopic Mass:
248.978g/mol
Topological Polar Surface Area:
12.9A^2
Heavy Atom Count:
15
Formal Charge:
0
Complexity:
225
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information


GHS Pictogram:
N/A
Signal Word:
UN#:
-
Hazard Statements:
-
Precautionary Statements:
Class:
-
Packing Group:
-

NMR Spectrum


Other Analytical Data


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Chemical Structure



2-Chloro-3,6-bis(trifluoromethyl)pyridine, also known as $name$, is a valuable reagent widely employed in chemical synthesis. This compound serves as a versatile building block in organic chemistry, particularly in the preparation of pharmaceuticals, agrochemicals, and specialty chemicals. Its unique structure, featuring both chlorine and trifluoromethyl functional groups on a pyridine ring, imparts distinct properties that are advantageous in various synthetic routes.In chemical synthesis, $name$ is commonly used to introduce specific functional groups or moieties into organic molecules. The presence of the chloro and trifluoromethyl groups enables selective and efficient derivatization reactions, allowing chemists to tailor the properties of target compounds for desired applications. Additionally, the pyridine ring provides a rigid and conjugated structure that can influence the reactivity and properties of the final products.Moreover, the electron-withdrawing nature of the trifluoromethyl groups in 2-Chloro-3,6-bis(trifluoromethyl)pyridine enhances the acidity of nearby protons, making it a useful reagent in various transformations such as nucleophilic substitutions, metal-catalyzed reactions, and cross-coupling reactions. This compound's synthetic utility extends to the construction of complex organic molecules with high efficiency and precision, making it a valuable tool for synthetic chemists in both academic and industrial settings.Overall, the application of 2-Chloro-3,6-bis(trifluoromethyl)pyridine in chemical synthesis underscores its significance as a key intermediate in the preparation of diverse organic compounds with tailored properties and functionalities.