1. Home
  2. [2-(2-trimethylsilylethoxymethyl)pyrazol-3-yl]boronic acid

Contact Angene

Tel: +852 8191 6999

Email: [email protected]

Brc1cnc(nc1)C
Pyrimidine, 5-bromo-2-methyl-
CCCP1(=O)OP(=O)(CCC)OP(=O)(O1)CCC
1,3,5,2,4,6-Trioxatriphosphorinane, 2,4,6-tripropyl-, 2,4,6-trioxide
CC1(C)OB(OC1(C)C)B1OC(C(O1)(C)C)(C)C
2,2'-Bi-1,3,2-dioxaborolane, 4,4,4',4',5,5,5',5'-octamethyl-
O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.[Pd].[Pd]
Tris(dibenzylideneacetone)dipalladium
C1CCC(CC1)P(C1CCCCC1)C1CCCCC1.Cc1cc(C)c(c(c1)C)N1CCN(C1=[Ru](=Cc1ccccc1)(Cl)Cl)c1c(C)cc(cc1C)C
Ruthenium,[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)-, (SP-5-41)-

[2-(2-trimethylsilylethoxymethyl)pyrazol-3-yl]boronic acid

OB(c1ccnn1COCC[Si](C)(C)C)O Request for Quotation
Chemical Name: [2-(2-trimethylsilylethoxymethyl)pyrazol-3-yl]boronic acid
CAS Number: 188978-71-4
Product Number: AG002HNC(AGN-PC-03H11F)
Synonyms:
MDL No:
Molecular Formula: C9H19BN2O3Si
Molecular Weight: 242.1553

Identification/Properties

Properties
Storage:
Keep in dry area;2-8℃;
Form:
Solid
Computed Properties
Molecular Weight:
242.157g/mol
Hydrogen Bond Donor Count:
2
Hydrogen Bond Acceptor Count:
4
Rotatable Bond Count:
6
Exact Mass:
242.126g/mol
Monoisotopic Mass:
242.126g/mol
Topological Polar Surface Area:
67.5A^2
Heavy Atom Count:
16
Formal Charge:
0
Complexity:
213
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information

GHS Pictogram:
N/A
Signal Word:
UN#:
-
Hazard Statements:
-
Precautionary Statements:
Class:
-
Packing Group:
-

NMR Spectrum

Other Analytical Data

Request for Quotation

Customer Feedback

Chemical Structure


The (1-((2-(Trimethylsilyl)ethoxy)methyl)-1H-pyrazol-5-yl)boronic acid is a versatile and valuable compound in chemical synthesis. It serves as a key building block in organic reactions, particularly in the field of cross-coupling reactions. By acting as a boronic acid reagent, this compound enables the formation of carbon-carbon bonds, which is crucial for the synthesis of complex organic molecules.One of the primary applications of (1-((2-(Trimethylsilyl)ethoxy)methyl)-1H-pyrazol-5-yl)boronic acid is in Suzuki-Miyaura cross-coupling reactions. In these reactions, the boronic acid functionality of this compound reacts with organic halides or pseudohalides in the presence of a palladium catalyst to form new carbon-carbon bonds. This process allows chemists to efficiently construct biaryl compounds, which are prevalent in pharmaceuticals, agrochemicals, and materials science.Additionally, (1-((2-(Trimethylsilyl)ethoxy)methyl)-1H-pyrazol-5-yl)boronic acid can be utilized in other types of cross-coupling reactions, such as Buchwald-Hartwig amination and Stille coupling. These reactions enable the selective functionalization of organic molecules, thereby facilitating the synthesis of diverse compounds with specific properties and functionalities.Overall, the versatility and reactivity of (1-((2-(Trimethylsilyl)ethoxy)methyl)-1H-pyrazol-5-yl)boronic acid make it a valuable tool for organic chemists engaged in the synthesis of complex molecules for various applications.