3-(2-hydroxyethyl)piperazin-2-one


Chemical Name: 3-(2-hydroxyethyl)piperazin-2-one
CAS Number: 936940-62-4
Product Number: AG00GVGV(AGN-PC-03XBE2)
Synonyms:
MDL No:
Molecular Formula: C6H12N2O2
Molecular Weight: 144.1717

Identification/Properties


Computed Properties
Molecular Weight:
144.174g/mol
XLogP3:
-1.4
Hydrogen Bond Donor Count:
3
Hydrogen Bond Acceptor Count:
3
Rotatable Bond Count:
2
Exact Mass:
144.09g/mol
Monoisotopic Mass:
144.09g/mol
Topological Polar Surface Area:
61.4A^2
Heavy Atom Count:
10
Formal Charge:
0
Complexity:
127
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
1
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information


GHS Pictogram:
N/A
Signal Word:
UN#:
-
Hazard Statements:
-
Precautionary Statements:
Class:
-
Packing Group:
-

NMR Spectrum


Other Analytical Data


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Chemical Structure



3-(2-Hydroxyethyl)piperazin-2-one is a versatile compound widely used in chemical synthesis as a key building block in the production of pharmaceuticals, agrochemicals, and specialty chemicals. Its unique structure allows for diverse functionalization, making it a valuable intermediate in organic synthesis.In chemical reactions, 3-(2-Hydroxyethyl)piperazin-2-one can serve as a nucleophile, participating in substitution and addition reactions to introduce various functional groups. Its piperazinone ring provides a stable scaffold for further modifications, allowing for the incorporation of different chemical moieties.Additionally, the hydroxyethyl group on the piperazinone ring enhances the compound's solubility and reactivity in aqueous systems, making it particularly useful in reactions that require water as a solvent. This property expands the applications of 3-(2-Hydroxyethyl)piperazin-2-one to include aqueous-phase chemistry and bioconjugation reactions.Overall, the versatility and reactivity of 3-(2-Hydroxyethyl)piperazin-2-one make it a valuable tool in chemical synthesis, enabling the construction of complex molecules with diverse functionalities for various industrial applications.