1. Home
  2. N-hydroxy-1-[(4-methoxyphenyl)methyl]indole-6-carboxamide

Contact Angene

Tel: +852 8191 6999

Email: [email protected]

Brc1cnc(nc1)C
Pyrimidine, 5-bromo-2-methyl-
CCCP1(=O)OP(=O)(CCC)OP(=O)(O1)CCC
1,3,5,2,4,6-Trioxatriphosphorinane, 2,4,6-tripropyl-, 2,4,6-trioxide
CC1(C)OB(OC1(C)C)B1OC(C(O1)(C)C)(C)C
2,2'-Bi-1,3,2-dioxaborolane, 4,4,4',4',5,5,5',5'-octamethyl-
O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.[Pd].[Pd]
Tris(dibenzylideneacetone)dipalladium
C1CCC(CC1)P(C1CCCCC1)C1CCCCC1.Cc1cc(C)c(c(c1)C)N1CCN(C1=[Ru](=Cc1ccccc1)(Cl)Cl)c1c(C)cc(cc1C)C
Ruthenium,[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)-, (SP-5-41)-

N-hydroxy-1-[(4-methoxyphenyl)methyl]indole-6-carboxamide

ONC(=O)c1ccc2c(c1)n(cc2)Cc1ccc(cc1)OC Request for Quotation
Chemical Name: N-hydroxy-1-[(4-methoxyphenyl)methyl]indole-6-carboxamide
CAS Number: 950762-95-5
Product Number: AG00IIQ1(AGN-PC-04QNWY)
Synonyms:
MDL No:
Molecular Formula: C17H16N2O3
Molecular Weight: 296.3205

Identification/Properties

Computed Properties
Molecular Weight:
296.326g/mol
XLogP3:
2.4
Hydrogen Bond Donor Count:
2
Hydrogen Bond Acceptor Count:
3
Rotatable Bond Count:
4
Exact Mass:
296.116g/mol
Monoisotopic Mass:
296.116g/mol
Topological Polar Surface Area:
63.5A^2
Heavy Atom Count:
22
Formal Charge:
0
Complexity:
382
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information

NMR Spectrum

Other Analytical Data

Request for Quotation

Customer Feedback

Chemical Structure


PCI-34051 is a potent and selective inhibitor of histone deacetylase 8 (HDAC8), a key enzyme involved in epigenetic regulation. In chemical synthesis, PCI-34051 can be utilized to modify the acetylation status of histones, which can modulate gene expression and impact various cellular processes. By targeting HDAC8, PCI-34051 can influence the acetylation levels of histones, leading to changes in chromatin structure and gene transcription. This can be particularly useful in studying the role of epigenetic modifications in disease states or in the development of novel therapeutic strategies. Additionally, PCI-34051's specificity for HDAC8 makes it a valuable tool for dissecting the biological functions of this particular histone deacetylase isoform in chemical synthesis applications.