methyl 6-[(2-methylpropan-2-yl)oxycarbonylamino]-1H-indole-4-carboxylate


Chemical Name: methyl 6-[(2-methylpropan-2-yl)oxycarbonylamino]-1H-indole-4-carboxylate
CAS Number: 731810-56-3
Product Number: AG00635I(AGN-PC-059B8Y)
Synonyms:
MDL No:
Molecular Formula: C15H18N2O4
Molecular Weight: 290.3144

Identification/Properties


Safety Information


GHS Pictogram:
Signal Word:
Warning
UN#:
N/A
Hazard Statements:
H302-H315-H319-H335
Precautionary Statements:
P261-P305+P351+P338
Class:
N/A
Packing Group:
N/A

NMR Spectrum


Other Analytical Data


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Chemical Structure



Methyl 6-((tert-butoxycarbonyl)amino)-1H-indole-4-carboxylate is a versatile compound widely used in chemical synthesis processes. Its application in organic chemistry primarily revolves around its unique functional groups and reactivity.This compound serves as a valuable building block in the synthesis of complex organic molecules due to its ability to undergo various chemical transformations. The tert-butoxycarbonyl (Boc) protecting group provides stability to the amino group, allowing selective reactions to occur at other sites without affecting the desired functionality. The indole core adds aromatic properties and can participate in different aromatic substitution reactions.In peptide synthesis, Methyl 6-((tert-butoxycarbonyl)amino)-1H-indole-4-carboxylate can be utilized as a key intermediate for introducing indole-containing amino acids into peptide chains. The Boc protection ensures that the amino group remains unaltered during peptide coupling reactions, enabling precise control over the peptide sequence. Furthermore, the presence of the ester group facilitates peptide bond formation through coupling with amino acids or peptide fragments.Overall, Methyl 6-((tert-butoxycarbonyl)amino)-1H-indole-4-carboxylate plays a crucial role in the efficient synthesis of bioactive compounds, pharmaceuticals, and peptides, showcasing its significance in advancing chemical synthesis methodologies.