6-bromo-4-methylpyridine-3-carbonitrile


Chemical Name: 6-bromo-4-methylpyridine-3-carbonitrile
CAS Number: 1003711-35-0
Product Number: AG0001SP(AGN-PC-05IUB0)
Synonyms:
MDL No:
Molecular Formula: C7H5BrN2
Molecular Weight: 197.0320

Identification/Properties


Computed Properties
Molecular Weight:
197.035g/mol
XLogP3:
2
Hydrogen Bond Donor Count:
0
Hydrogen Bond Acceptor Count:
2
Rotatable Bond Count:
0
Exact Mass:
195.964g/mol
Monoisotopic Mass:
195.964g/mol
Topological Polar Surface Area:
36.7A^2
Heavy Atom Count:
10
Formal Charge:
0
Complexity:
160
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

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Chemical Structure



2-Bromo-5-cyano-4-picoline, also referred to as BCPL, is a valuable intermediate commonly used in organic chemical synthesis. Its unique molecular structure makes it a versatile building block in the production of various pharmaceuticals, agrochemicals, and specialty chemicals.One of the key applications of 2-Bromo-5-cyano-4-picoline is its utility as a precursor in the synthesis of biologically active compounds. By incorporating BCPL into synthetic pathways, chemists can introduce specific functional groups at strategic positions in the target molecules, enhancing their potency and selectivity. This compound's bromine and cyano substituents can serve as essential reaction handles for further derivatization, allowing for the creation of structurally diverse and potentially bioactive molecules.Furthermore, 2-Bromo-5-cyano-4-picoline plays a vital role in transition metal-catalyzed cross-coupling reactions. Its electron-rich pyridine ring facilitates coordination with metal catalysts such as palladium or nickel, enabling efficient carbon-carbon or carbon-heteroatom bond formation. This reactivity makes BCPL a valuable tool for the construction of complex molecular frameworks with high synthetic efficiency.Overall, the application of 2-Bromo-5-cyano-4-picoline in chemical synthesis provides chemists with a powerful means to access structurally diverse and pharmacologically relevant compounds, driving innovation in drug discovery and materials science.