1. Home
  2. tert-butyl 3-bromo-5-methylindole-1-carboxylate

Contact Angene

Tel: +852 8191 6999

Email: [email protected]

Brc1cnc(nc1)C
Pyrimidine, 5-bromo-2-methyl-
CCCP1(=O)OP(=O)(CCC)OP(=O)(O1)CCC
1,3,5,2,4,6-Trioxatriphosphorinane, 2,4,6-tripropyl-, 2,4,6-trioxide
CC1(C)OB(OC1(C)C)B1OC(C(O1)(C)C)(C)C
2,2'-Bi-1,3,2-dioxaborolane, 4,4,4',4',5,5,5',5'-octamethyl-
O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.[Pd].[Pd]
Tris(dibenzylideneacetone)dipalladium
C1CCC(CC1)P(C1CCCCC1)C1CCCCC1.Cc1cc(C)c(c(c1)C)N1CCN(C1=[Ru](=Cc1ccccc1)(Cl)Cl)c1c(C)cc(cc1C)C
Ruthenium,[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)-, (SP-5-41)-

tert-butyl 3-bromo-5-methylindole-1-carboxylate

Cc1ccc2c(c1)c(Br)cn2C(=O)OC(C)(C)C Request for Quotation
Chemical Name: tert-butyl 3-bromo-5-methylindole-1-carboxylate
CAS Number: 914349-24-9
Product Number: AG00IGOL(AGN-PC-05W61Y)
Synonyms:
MDL No:
Molecular Formula: C14H16BrNO2
Molecular Weight: 310.1863

Identification/Properties

Computed Properties
Molecular Weight:
310.191g/mol
XLogP3:
4.3
Hydrogen Bond Donor Count:
0
Hydrogen Bond Acceptor Count:
2
Rotatable Bond Count:
2
Exact Mass:
309.036g/mol
Monoisotopic Mass:
309.036g/mol
Topological Polar Surface Area:
31.2A^2
Heavy Atom Count:
18
Formal Charge:
0
Complexity:
326
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information

GHS Pictogram:
N/A
Signal Word:
UN#:
-
Hazard Statements:
-
Precautionary Statements:
Class:
-
Packing Group:
-

NMR Spectrum

Other Analytical Data

Request for Quotation

Customer Feedback

Chemical Structure


1-Boc-3-bromo-5-methylindole is a versatile chemical compound that finds wide application in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Its unique structure offers several key advantages in chemical transformations, making it a valuable building block for the synthesis of diverse molecular structures.Due to the presence of the Boc (tert-butoxycarbonyl) protecting group, 1-Boc-3-bromo-5-methylindole serves as an effective precursor in the preparation of various indole derivatives. The Boc group can be easily removed under mild conditions, allowing for further functionalization of the molecule. Furthermore, the bromo substituent enables straightforward introduction of additional functional groups through cross-coupling reactions, such as Suzuki-Miyaura and Heck couplings.In pharmaceutical research, 1-Boc-3-bromo-5-methylindole has been employed in the synthesis of bioactive compounds with potential therapeutic activities. By utilizing this compound as a key intermediate, chemists can access a wide range of indole-containing molecules that exhibit diverse pharmacological properties. Its structural flexibility and ease of manipulation make it a valuable tool for the preparation of drug candidates and molecular probes in medicinal chemistry.Moreover, in the field of agrochemical development, 1-Boc-3-bromo-5-methylindole serves as a crucial starting material for the synthesis of novel pesticides and crop protection agents. Through strategic modification of its molecular structure, chemists can design new pesticide molecules with enhanced efficacy and reduced environmental impact. This compound's versatility and compatibility with various synthetic methodologies make it a valuable asset in the quest for innovative solutions in agriculture.In conclusion, 1-Boc-3-bromo-5-methylindole plays a vital role in chemical synthesis, offering a myriad of opportunities for the construction of complex organic molecules with diverse applications in pharmaceuticals and agrochemicals. Its utility as a key building block underscores its importance in modern synthetic chemistry and underscores its significance in the development of new materials and bioactive compounds.