2,2,2-trifluoro-1-pyridin-2-ylethanamine;hydrochloride


Chemical Name: 2,2,2-trifluoro-1-pyridin-2-ylethanamine;hydrochloride
CAS Number: 1187929-38-9
Product Number: AG0080WX(AGN-PC-09RR0M)
Synonyms:
MDL No:
Molecular Formula: C7H8ClF3N2
Molecular Weight: 212.6000

Identification/Properties


Computed Properties
Molecular Weight:
212.6g/mol
Hydrogen Bond Donor Count:
2
Hydrogen Bond Acceptor Count:
5
Rotatable Bond Count:
1
Exact Mass:
212.033g/mol
Monoisotopic Mass:
212.033g/mol
Topological Polar Surface Area:
38.9A^2
Heavy Atom Count:
13
Formal Charge:
0
Complexity:
146
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
1
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
2
Compound Is Canonicalized:
Yes

Safety Information


GHS Pictogram:
N/A
Signal Word:
UN#:
N/A
Hazard Statements:
-
Precautionary Statements:
Class:
N/A
Packing Group:
N/A

NMR Spectrum


Other Analytical Data


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Chemical Structure



2,2,2-Trifluoro-1-(pyridin-2-yl)ethanamine hydrochloride, commonly referred to as $name$, plays a crucial role in chemical synthesis as a versatile building block. Utilized in a wide range of reactions, this compound serves as a key intermediate in the production of various pharmaceuticals, agrochemicals, and advanced materials.In organic synthesis, $name$ serves as a valuable precursor in the creation of complex molecules due to its unique chemical properties. Its trifluoromethyl group and pyridine moiety enable the introduction of fluorine-containing functional groups, enhancing the bioactivity and stability of the final products. Furthermore, the presence of the amine group allows for facile derivatization and incorporation into diverse molecular scaffolds.In the development of pharmaceutical compounds, 2,2,2-Trifluoro-1-(pyridin-2-yl)ethanamine hydrochloride is used to introduce fluorine atoms into drug molecules, enhancing their potency, metabolic stability, and bioavailability. Its application in medicinal chemistry enables the synthesis of novel drug candidates with improved pharmacokinetic profiles and enhanced therapeutic effects.Moreover, in agrochemical research, this compound serves as a valuable tool for the design and synthesis of crop protection agents and herbicides. The trifluoromethyl group imparts desirable properties to agrochemical molecules, such as increased lipophilicity and resistance to metabolic degradation, leading to enhanced efficacy and prolonged action in the field.Overall, 2,2,2-Trifluoro-1-(pyridin-2-yl)ethanamine hydrochloride's significance in chemical synthesis lies in its ability to facilitate the construction of diverse chemical structures with enhanced properties for pharmaceutical, agrochemical, and material science applications.