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Brc1cnc(nc1)C
Pyrimidine, 5-bromo-2-methyl-
CCCP1(=O)OP(=O)(CCC)OP(=O)(O1)CCC
1,3,5,2,4,6-Trioxatriphosphorinane, 2,4,6-tripropyl-, 2,4,6-trioxide
CC1(C)OB(OC1(C)C)B1OC(C(O1)(C)C)(C)C
2,2'-Bi-1,3,2-dioxaborolane, 4,4,4',4',5,5,5',5'-octamethyl-
O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.[Pd].[Pd]
Tris(dibenzylideneacetone)dipalladium
C1CCC(CC1)P(C1CCCCC1)C1CCCCC1.Cc1cc(C)c(c(c1)C)N1CCN(C1=[Ru](=Cc1ccccc1)(Cl)Cl)c1c(C)cc(cc1C)C
Ruthenium,[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)-, (SP-5-41)-

8-bromo-2-chloro-6-fluoroquinazoline

Fc1cc(Br)c2c(c1)cnc(n2)Cl Request for Quotation
Chemical Name: 8-bromo-2-chloro-6-fluoroquinazoline
CAS Number: 953039-63-9
Product Number: AG006O4A(AGN-PC-0CSNJK)
Synonyms:
MDL No:
Molecular Formula: C8H3BrClFN2
Molecular Weight: 261.4782

Identification/Properties

Properties
Storage:
Inert atmosphere;-10 ℃;
Form:
Solid
Computed Properties
Molecular Weight:
261.478g/mol
XLogP3:
3.3
Hydrogen Bond Donor Count:
0
Hydrogen Bond Acceptor Count:
3
Rotatable Bond Count:
0
Exact Mass:
259.915g/mol
Monoisotopic Mass:
259.915g/mol
Topological Polar Surface Area:
25.8A^2
Heavy Atom Count:
13
Formal Charge:
0
Complexity:
195
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information

GHS Pictogram:
Signal Word:
Warning
UN#:
-
Hazard Statements:
H315-H319-H335
Precautionary Statements:
P261-P305+P351+P338
Class:
-
Packing Group:
-

NMR Spectrum

Other Analytical Data

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Chemical Structure


8-Bromo-2-chloro-6-fluoroquinazoline is a versatile building block commonly used in chemical synthesis. Its unique molecular structure makes it a valuable intermediate in the production of various pharmaceuticals, agrochemicals, and other fine chemicals. This compound is particularly valued for its ability to serve as a key precursor in the synthesis of complex heterocyclic compounds.In organic chemistry, 8-Bromo-2-chloro-6-fluoroquinazoline is frequently employed as a halogenated quinazoline derivative, allowing for facile functionalization and manipulation of its chemical properties. Its bromo, chloro, and fluoro substituents offer diverse reactivity profiles that enable the formation of a wide range of novel structures. This compound is often utilized as a starting material for the construction of biologically active molecules with potential therapeutic applications.Furthermore, 8-Bromo-2-chloro-6-fluoroquinazoline plays a crucial role in the development of new drug candidates and agrochemicals due to its ability to participate in various synthetic transformations, including cross-coupling reactions, nucleophilic substitutions, and heterocyclic ring formations. Its presence in the molecular scaffold of target compounds can impart desirable properties such as enhanced potency, selectivity, and pharmacokinetic profiles.Overall, the application of 8-Bromo-2-chloro-6-fluoroquinazoline in chemical synthesis showcases its significance as a versatile intermediate with immense potential for enabling the efficient and scalable production of structurally diverse and functionally important molecules.