1. Home
  2. 5-(2-fluoropyridin-4-yl)-2-phenylmethoxy-N-pyridin-3-ylbenzamide

Contact Angene

Tel: +852 8191 6999

Email: [email protected]

Brc1cnc(nc1)C
Pyrimidine, 5-bromo-2-methyl-
CCCP1(=O)OP(=O)(CCC)OP(=O)(O1)CCC
1,3,5,2,4,6-Trioxatriphosphorinane, 2,4,6-tripropyl-, 2,4,6-trioxide
CC1(C)OB(OC1(C)C)B1OC(C(O1)(C)C)(C)C
2,2'-Bi-1,3,2-dioxaborolane, 4,4,4',4',5,5,5',5'-octamethyl-
O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.[Pd].[Pd]
Tris(dibenzylideneacetone)dipalladium
C1CCC(CC1)P(C1CCCCC1)C1CCCCC1.Cc1cc(C)c(c(c1)C)N1CCN(C1=[Ru](=Cc1ccccc1)(Cl)Cl)c1c(C)cc(cc1C)C
Ruthenium,[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)-, (SP-5-41)-

5-(2-fluoropyridin-4-yl)-2-phenylmethoxy-N-pyridin-3-ylbenzamide

Fc1nccc(c1)c1ccc(c(c1)C(=O)Nc1cccnc1)OCc1ccccc1 Request for Quotation
Chemical Name: 5-(2-fluoropyridin-4-yl)-2-phenylmethoxy-N-pyridin-3-ylbenzamide
CAS Number: 1285515-21-0
Product Number: AG000Y6K(AGN-PC-0HQXXN)
Synonyms:
MDL No:
Molecular Formula: C24H18FN3O2
Molecular Weight: 399.4170

Identification/Properties

Computed Properties
Molecular Weight:
399.425g/mol
XLogP3:
4.1
Hydrogen Bond Donor Count:
1
Hydrogen Bond Acceptor Count:
5
Rotatable Bond Count:
6
Exact Mass:
399.138g/mol
Monoisotopic Mass:
399.138g/mol
Topological Polar Surface Area:
64.1A^2
Heavy Atom Count:
30
Formal Charge:
0
Complexity:
543
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information

NMR Spectrum

Other Analytical Data

Request for Quotation

Customer Feedback

Chemical Structure


GSK2578215A is a highly versatile compound that finds extensive application in chemical synthesis. As a potent and selective inhibitor of nicotinamide adenine dinucleotide (NAD+) biosynthesis enzyme nicotinamide phosphoribosyltransferase (NAMPT), this compound plays a crucial role in regulating cellular metabolism and maintaining energy homeostasis. In chemical synthesis, GSK2578215A is utilized for its ability to modulate NAD+ levels, which can impact various metabolic pathways in cells.By inhibiting NAMPT, GSK2578215A can disrupt the NAD+ salvage pathway, leading to a reduction in cellular NAD+ levels. This alteration in NAD+ metabolism can have profound effects on cellular functions, such as DNA repair, gene expression, and energy production. In synthetic chemistry, the controlled modulation of NAD+ levels using GSK2578215A can be exploited to study metabolic pathways and investigate cellular processes.Furthermore, the unique mechanism of action of GSK2578215A allows for the exploration of NAD+-dependent pathways in chemical reactions, offering new opportunities for designing innovative synthetic strategies. Its role in regulating cellular metabolism makes GSK2578215A a valuable tool for chemical biologists and medicinal chemists seeking to develop novel compounds targeting NAD+ metabolism for therapeutic purposes.