Chemical Name: | (3-fluoropyridin-2-yl) trifluoromethanesulfonate |
CAS Number: | 1310559-92-2 |
Product Number: | AG0073EM(AGN-PC-0J0Y9M) |
Synonyms: | |
MDL No: | |
Molecular Formula: | C6H3F4NO3S |
Molecular Weight: | 245.1515 |
3-Fluoropyridin-2-yl trifluoromethanesulfonate, also known as $name$, is a versatile reagent widely used in organic synthesis to introduce the trifluoromethanesulfonyl (triflate) group onto various functional groups. This compound serves as a robust trifluoromethanesulfonylating agent that enables chemists to carry out efficient and selective transformations in a variety of synthetic protocols.In chemical synthesis, 3-Fluoropyridin-2-yl trifluoromethanesulfonate plays a crucial role in cross-coupling reactions, particularly in Suzuki-Miyaura and Heck couplings, where it serves as a valuable tool for the functionalization of aryl and heteroaryl compounds. The triflate moiety is known for its excellent leaving group ability, facilitating carbon-carbon bond formation under mild reaction conditions.Additionally, this reagent is utilized in the synthesis of pharmaceuticals, agrochemicals, and materials science applications due to its ability to install the triflate group selectively at strategic positions in complex molecules. Its compatibility with a wide range of substrates and its stability make it a preferred choice for synthetic chemists aiming to streamline their processes and access novel chemical space.Overall, the application of 3-Fluoropyridin-2-yl trifluoromethanesulfonate in chemical synthesis offers a powerful and practical tool for the construction of diverse molecular structures with enhanced functionality and reactivity.