1-Propanone, 1-(2-hydroxy-5-methylphenyl)-


Chemical Name: 1-Propanone, 1-(2-hydroxy-5-methylphenyl)-
CAS Number: 938-45-4
Product Number: AG003GA4(AGN-PC-0JL9LX)
Synonyms:
MDL No:
Molecular Formula: C10H12O2
Molecular Weight: 164.2011

Identification/Properties


Properties
Form:
Liquid
Computed Properties
Molecular Weight:
164.204g/mol
XLogP3:
2.9
Hydrogen Bond Donor Count:
1
Hydrogen Bond Acceptor Count:
2
Rotatable Bond Count:
2
Exact Mass:
164.084g/mol
Monoisotopic Mass:
164.084g/mol
Topological Polar Surface Area:
37.3A^2
Heavy Atom Count:
12
Formal Charge:
0
Complexity:
165
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

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NMR Spectrum


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Chemical Structure



2′-Hydroxy-5′-methylpropiophenone, also known as HMPP, is a versatile compound widely used in chemical synthesis processes. Its primary application lies in its role as a key intermediate in the synthesis of various pharmaceuticals, agrochemicals, and fine chemicals. HMPP serves as a crucial building block owing to its unique molecular structure, which enables it to participate in diverse chemical reactions for the production of complex organic molecules. Specifically, HMPP can undergo reactions such as acylation, alkylation, and condensation to introduce functional groups and form new carbon-carbon or carbon-heteroatom bonds.In pharmaceutical synthesis, 2′-Hydroxy-5′-methylpropiophenone is often utilized for the preparation of drugs with therapeutic properties. Its presence in the synthetic pathway can influence the stereochemistry, pharmacokinetics, and overall efficacy of the final pharmaceutical product. Furthermore, HMPP's compatibility with various reaction conditions and reagents makes it a valuable tool for chemists seeking to streamline the synthesis of target compounds.Beyond the realm of pharmaceuticals, HMPP finds applications in the agrochemical industry, where it contributes to the creation of crop protection agents and herbicides. By incorporating 2′-Hydroxy-5′-methylpropiophenone into the synthetic route of agrochemicals, chemists can design molecules with enhanced biological activity and reduced environmental impact.Overall, the versatile nature and reactivity of 2′-Hydroxy-5′-methylpropiophenone make it a vital component in chemical synthesis, enabling the efficient construction of complex molecules with diverse applications across various industries.