Pyrrolidine, 1-(trimethylsilyl)-


Chemical Name: Pyrrolidine, 1-(trimethylsilyl)-
CAS Number: 15097-49-1
Product Number: AG001MYN(AGN-PC-0JLVAY)
Synonyms:
MDL No:
Molecular Formula: C7H17NSi
Molecular Weight: 143.3021

Identification/Properties


Computed Properties
Molecular Weight:
143.305g/mol
Hydrogen Bond Donor Count:
0
Hydrogen Bond Acceptor Count:
1
Rotatable Bond Count:
1
Exact Mass:
143.113g/mol
Monoisotopic Mass:
143.113g/mol
Topological Polar Surface Area:
3.2A^2
Heavy Atom Count:
9
Formal Charge:
0
Complexity:
89.6
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

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Chemical Structure



1-(Trimethylsilyl)pyrrolidine, a versatile reagent in chemical synthesis, is widely utilized as a key building block in organic chemistry. Its unique structure with the trimethylsilyl group attached to the pyrrolidine nitrogen atom imparts beneficial properties that make it a valuable tool for various transformations.In organic synthesis, 1-(Trimethylsilyl)pyrrolidine can act as a nucleophilic reagent in a range of reactions. It can participate in nucleophilic substitution reactions, such as alkylation and acylation, leading to the formation of new carbon-carbon or carbon-heteroatom bonds. Additionally, its reactivity in cycloaddition reactions enables the construction of complex ring systems efficiently.Furthermore, 1-(Trimethylsilyl)pyrrolidine is employed in asymmetric synthesis as a chiral auxiliary, facilitating the synthesis of enantiomerically pure compounds. By controlling the stereochemistry during transformations, this reagent plays a vital role in accessing optically active molecules with high selectivity.Overall, the utility of 1-(Trimethylsilyl)pyrrolidine in chemical synthesis extends to diverse applications, showcasing its significance as a valuable reagent for organic chemists seeking efficient routes to complex molecular structures.