Chemical Name: | Phosphonic acid, benzoyl-, diethyl ester |
CAS Number: | 3277-27-8 |
Product Number: | AG003PG8(AGN-PC-0JNA25) |
Synonyms: | |
MDL No: | |
Molecular Formula: | C11H15O4P |
Molecular Weight: | 242.208161 |
Diethyl benzoylphosphonate, commonly known as DEBP, is a versatile compound widely used in chemical synthesis. Its primary application lies in the formation of C-C and C-N bonds through the Horner-Wadsworth-Emmons reaction, a powerful tool in organic synthesis. By reacting with aldehydes or ketones in the presence of a base, DEBP serves as a precursor for the efficient and selective preparation of unsaturated esters and amides.Additionally, DEBP is employed in the construction of various heterocyclic structures, such as pyrazoles and pyrimidines, due to its ability to introduce phosphonate ester groups into the target molecules. This not only allows for the modulation of the physicochemical properties of the final compounds but also facilitates further functionalization through subsequent transformations.Moreover, Diethyl benzoylphosphonate can also participate in the synthesis of pharmaceutical intermediates and agrochemicals, showcasing its significance in the development of diverse bioactive compounds. Its ease of handling and compatibility with a wide range of functional groups make DEBP a valuable building block in the arsenal of synthetic chemists striving to access complex molecular architectures efficiently and selectively.