2-Furanpropanoic acid, tetrahydro-


Chemical Name: 2-Furanpropanoic acid, tetrahydro-
CAS Number: 935-12-6
Product Number: AG00GSU6(AGN-PC-0JNXS8)
Synonyms:
MDL No:
Molecular Formula: C7H12O3
Molecular Weight: 144.1684

Identification/Properties


Computed Properties
Molecular Weight:
144.17g/mol
XLogP3:
0.5
Hydrogen Bond Donor Count:
1
Hydrogen Bond Acceptor Count:
3
Rotatable Bond Count:
3
Exact Mass:
144.079g/mol
Monoisotopic Mass:
144.079g/mol
Topological Polar Surface Area:
46.5A^2
Heavy Atom Count:
10
Formal Charge:
0
Complexity:
122
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
1
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information


GHS Pictogram:
N/A
Signal Word:
UN#:
-
Hazard Statements:
-
Precautionary Statements:
Class:
-
Packing Group:
-

NMR Spectrum


Other Analytical Data


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Chemical Structure



3-(Tetrahydrofuran-2-yl)propionic acid, also known as THF-2-propionic acid, is a versatile compound widely used in chemical synthesis. It serves as a crucial building block in the production of various pharmaceuticals, agrochemicals, and fine chemicals. Due to its unique structure containing both a tetrahydrofuran ring and a propionic acid moiety, this compound offers opportunities for diverse chemical transformations and functional group interconversions. In chemical synthesis, 3-(Tetrahydrofuran-2-yl)propionic acid can be employed as a key intermediate in the preparation of various heterocyclic compounds, such as pyrroles, tetrahydrofurans, and lactones. Its ability to undergo selective functionalization reactions at both the tetrahydrofuran ring and the propionic acid group makes it a valuable precursor for the synthesis of complex organic molecules. Moreover, the presence of a chiral center in the propionic acid moiety enables the synthesis of enantiomerically pure compounds, making it particularly useful in asymmetric synthesis strategies.Additionally, 3-(Tetrahydrofuran-2-yl)propionic acid can be utilized in the preparation of bioactive molecules, natural product derivatives, and advanced materials. Its versatile reactivity and compatibility with various reaction conditions make it a sought-after building block in the synthesis of drug candidates and agrochemicals with diverse pharmacological and biological activities. Overall, the application of 3-(Tetrahydrofuran-2-yl)propionic acid in chemical synthesis offers chemists a valuable tool to access structurally complex and functionally diverse compounds with broad applications in the fields of pharmaceuticals, materials science, and chemical research.