8-Quinolinol, 6-fluoro-


Chemical Name: 8-Quinolinol, 6-fluoro-
CAS Number: 135838-04-9
Product Number: AG00HUEK(AGN-PC-0JPYZJ)
Synonyms:
MDL No:
Molecular Formula: C9H6FNO
Molecular Weight: 163.1484

Identification/Properties


Computed Properties
Molecular Weight:
163.151g/mol
XLogP3:
2.1
Hydrogen Bond Donor Count:
1
Hydrogen Bond Acceptor Count:
3
Rotatable Bond Count:
0
Exact Mass:
163.043g/mol
Monoisotopic Mass:
163.043g/mol
Topological Polar Surface Area:
33.1A^2
Heavy Atom Count:
12
Formal Charge:
0
Complexity:
165
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

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Chemical Structure



6-Fluoroquinolin-8-ol, a versatile chemical compound, finds extensive application in chemical synthesis processes. Its unique structure, characterized by a fluorine atom and a hydroxyl group on a quinoline ring, imparts distinct reactivity and functionality that make it a valuable building block in the creation of various organic compounds.One key application of 6-Fluoroquinolin-8-ol is as a precursor in the synthesis of pharmaceutical compounds. Its fluorine atom can serve as a handle for further derivatization, allowing for the introduction of specific functional groups that are crucial for enhancing the biological activity or pharmacokinetic properties of the final drug molecule. Additionally, the hydroxyl group on the quinoline ring can participate in various chemical reactions, such as nucleophilic substitution or oxidation, leading to the formation of diverse molecular structures with potential therapeutic applications.Furthermore, 6-Fluoroquinolin-8-ol can be utilized as a ligand in coordination chemistry. Its ability to coordinate with metal ions opens up possibilities for the design and synthesis of metal complexes with tailored properties, such as catalytic activity or luminescence. By fine-tuning the ligand structure and metal center, researchers can access a wide range of coordination compounds with applications in materials science, catalysis, and other areas of chemical research.Overall, the strategic placement of the fluorine atom and hydroxyl group in 6-Fluoroquinolin-8-ol makes it a valuable tool in the hands of synthetic chemists, enabling the construction of complex molecules with precision and efficiency. Its diverse applications in pharmaceutical synthesis and coordination chemistry highlight its importance as a versatile building block in modern chemical research and development.