Boronic acid, [2,4-bis(phenylmethoxy)-5-pyrimidinyl]-


Chemical Name: Boronic acid, [2,4-bis(phenylmethoxy)-5-pyrimidinyl]-
CAS Number: 70523-24-9
Product Number: AG003FOQ(AGN-PC-0KK75G)
Synonyms:
MDL No:
Molecular Formula: C18H17BN2O4
Molecular Weight: 336.1496

Identification/Properties


Properties
MP:
88-91℃
BP:
600.4°C at 760 mmHg
Storage:
Keep in dry area;2-8℃;
Form:
Solid

Safety Information


GHS Pictogram:
Signal Word:
Warning
UN#:
-
Hazard Statements:
H315-H319-H335
Precautionary Statements:
P261-P305+P351+P338-P302+P352-P321-P405-P501
Class:
-
Packing Group:
-

NMR Spectrum


Other Analytical Data


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Chemical Structure



2,4-Bis(benzyloxy)pyrimidin-5-ylboronic acid is a versatile compound widely used in chemical synthesis as a key reagent in organic reactions. This compound plays a crucial role in cross-coupling reactions, specifically in Suzuki-Miyaura couplings, where it serves as a boronic acid source for the formation of carbon-carbon bonds. The boronic acid functionality in 2,4-Bis(benzyloxy)pyrimidin-5-ylboronic acid enables it to react with various electrophiles, such as aryl halides and triflates, leading to the efficient synthesis of biaryl compounds. Additionally, this compound is utilized in the preparation of heterocyclic structures and pharmaceutical intermediates due to its ability to undergo selective Suzuki coupling reactions under mild conditions. Its compatibility with a wide range of functional groups makes it an indispensable tool for chemists engaged in the synthesis of complex organic molecules.