Benzenesulfonamide, 4-bromo-2,5-difluoro-


Chemical Name: Benzenesulfonamide, 4-bromo-2,5-difluoro-
CAS Number: 214209-98-0
Product Number: AG003KVP(AGN-PC-0KKVBV)
Synonyms:
MDL No:
Molecular Formula: C6H4BrF2NO2S
Molecular Weight: 272.0673

Identification/Properties


Properties
MP:
167-169°C
BP:
354.7°C at 760 mmHg
Storage:
Keep in dry area;2-8℃;
Form:
Solid
Computed Properties
Molecular Weight:
272.064g/mol
XLogP3:
1.4
Hydrogen Bond Donor Count:
1
Hydrogen Bond Acceptor Count:
5
Rotatable Bond Count:
1
Exact Mass:
270.911g/mol
Monoisotopic Mass:
270.911g/mol
Topological Polar Surface Area:
68.5A^2
Heavy Atom Count:
13
Formal Charge:
0
Complexity:
279
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information


GHS Pictogram:
Signal Word:
Danger
UN#:
1759
Hazard Statements:
H314
Precautionary Statements:
P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P321-P363-P405-P501
Class:
8
Packing Group:

NMR Spectrum


Other Analytical Data


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Chemical Structure



4-Bromo-2,5-difluorobenzenesulfonamide is a versatile chemical compound widely used in chemical synthesis processes. With its unique structure and properties, this compound plays a crucial role in a variety of organic reactions and transformations. One key application of 4-Bromo-2,5-difluorobenzenesulfonamide is its usage as a valuable reagent in the synthesis of pharmaceutical intermediates. Its presence enables the introduction of specific functional groups into target molecules, allowing for the creation of new drugs or fine chemicals with enhanced biological activities.Furthermore, 4-Bromo-2,5-difluorobenzenesulfonamide is commonly employed in transition metal-catalyzed coupling reactions, such as Suzuki-Miyaura cross-coupling and Buchwald-Hartwig amination. These reactions are essential in modern organic synthesis for building complex molecular structures efficiently.Additionally, this compound can serve as a building block in the preparation of diverse heterocyclic compounds, which are significant in drug discovery and material science. Its incorporation into various synthetic pathways contributes to the development of innovative chemical entities with potential applications in pharmaceuticals, agrochemicals, and advanced materials.In summary, 4-Bromo-2,5-difluorobenzenesulfonamide is a valuable tool in chemical synthesis, enabling the efficient construction of molecular frameworks essential for the advancement of drug discovery, material science, and organic chemistry research.