1. Home
  2. Boronic acid, (5-methylbenzo[b]thien-2-yl)-

Contact Angene

Tel: +852 8191 6999

Email: [email protected]

Brc1cnc(nc1)C
Pyrimidine, 5-bromo-2-methyl-
CCCP1(=O)OP(=O)(CCC)OP(=O)(O1)CCC
1,3,5,2,4,6-Trioxatriphosphorinane, 2,4,6-tripropyl-, 2,4,6-trioxide
CC1(C)OB(OC1(C)C)B1OC(C(O1)(C)C)(C)C
2,2'-Bi-1,3,2-dioxaborolane, 4,4,4',4',5,5,5',5'-octamethyl-
O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.[Pd].[Pd]
Tris(dibenzylideneacetone)dipalladium
C1CCC(CC1)P(C1CCCCC1)C1CCCCC1.Cc1cc(C)c(c(c1)C)N1CCN(C1=[Ru](=Cc1ccccc1)(Cl)Cl)c1c(C)cc(cc1C)C
Ruthenium,[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)-, (SP-5-41)-

Boronic acid, (5-methylbenzo[b]thien-2-yl)-

Cc1ccc2c(c1)cc(s2)B(O)O Request for Quotation
Chemical Name: Boronic acid, (5-methylbenzo[b]thien-2-yl)-
CAS Number: 136099-65-5
Product Number: AG009BCR(AGN-PC-0KL703)
Synonyms:
MDL No:
Molecular Formula: C9H9BO2S
Molecular Weight: 192.0426

Identification/Properties

Computed Properties
Molecular Weight:
192.039g/mol
Hydrogen Bond Donor Count:
2
Hydrogen Bond Acceptor Count:
3
Rotatable Bond Count:
1
Exact Mass:
192.042g/mol
Monoisotopic Mass:
192.042g/mol
Topological Polar Surface Area:
68.7A^2
Heavy Atom Count:
13
Formal Charge:
0
Complexity:
189
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information

GHS Pictogram:
N/A
Signal Word:
UN#:
-
Hazard Statements:
-
Precautionary Statements:
Class:
-
Packing Group:
-

NMR Spectrum

Other Analytical Data

Request for Quotation

Customer Feedback

Chemical Structure


5-Methylbenzo[b]thiophene-2-boronic acid is a versatile building block in chemical synthesis due to its boronic acid functionality. Boronic acids are known for their ability to undergo various reactions with other compounds, making them valuable reagents in organic synthesis.One common application of 5-Methylbenzo[b]thiophene-2-boronic acid is in Suzuki-Miyaura cross-coupling reactions. In this reaction, the boronic acid moiety reacts with an aryl or heteroaryl halide in the presence of a palladium catalyst to form a new carbon-carbon bond. This reaction is widely used in the synthesis of pharmaceuticals, agrochemicals, and materials science.Additionally, 5-Methylbenzo[b]thiophene-2-boronic acid can be utilized in Buchwald-Hartwig amination reactions. In this transformation, the boronic acid reacts with an amine in the presence of a palladium catalyst to form a carbon-nitrogen bond. This type of reaction is valuable in the synthesis of amines, which are important structural motifs in many biologically active molecules.Furthermore, 5-Methylbenzo[b]thiophene-2-boronic acid can participate in Chan-Lam coupling reactions, where it reacts with a nitrogen nucleophile in the presence of a copper catalyst to form a carbon-nitrogen bond. This type of reaction is useful in the synthesis of heterocyclic compounds and pharmaceutical intermediates.Overall, 5-Methylbenzo[b]thiophene-2-boronic acid is a key tool in the toolbox of synthetic chemists, enabling the construction of complex molecular structures with high efficiency and selectivity.