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Brc1cnc(nc1)C
Pyrimidine, 5-bromo-2-methyl-
CCCP1(=O)OP(=O)(CCC)OP(=O)(O1)CCC
1,3,5,2,4,6-Trioxatriphosphorinane, 2,4,6-tripropyl-, 2,4,6-trioxide
CC1(C)OB(OC1(C)C)B1OC(C(O1)(C)C)(C)C
2,2'-Bi-1,3,2-dioxaborolane, 4,4,4',4',5,5,5',5'-octamethyl-
O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.[Pd].[Pd]
Tris(dibenzylideneacetone)dipalladium
C1CCC(CC1)P(C1CCCCC1)C1CCCCC1.Cc1cc(C)c(c(c1)C)N1CCN(C1=[Ru](=Cc1ccccc1)(Cl)Cl)c1c(C)cc(cc1C)C
Ruthenium,[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)-, (SP-5-41)-

Silane, [(4-bromophenyl)ethynyl]trimethyl-

Brc1ccc(cc1)C#C[Si](C)(C)C Request for Quotation
Chemical Name: Silane, [(4-bromophenyl)ethynyl]trimethyl-
CAS Number: 16116-78-2
Product Number: AG001S8N(AGN-PC-0L7JRA)
Synonyms:
MDL No:
Molecular Formula: C11H13BrSi
Molecular Weight: 253.2104

Identification/Properties

Properties
MP:
61-63 °C (lit.)
BP:
247.1 °C at 760 mmHg
Storage:
Keep in dry area;2-8℃;
Form:
Solid
Computed Properties
Molecular Weight:
253.214g/mol
Hydrogen Bond Donor Count:
0
Hydrogen Bond Acceptor Count:
0
Rotatable Bond Count:
2
Exact Mass:
251.997g/mol
Monoisotopic Mass:
251.997g/mol
Topological Polar Surface Area:
0A^2
Heavy Atom Count:
13
Formal Charge:
0
Complexity:
220
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information

GHS Pictogram:
Signal Word:
Warning
UN#:
-
Hazard Statements:
H302-H315-H319-H335
Precautionary Statements:
P261-P305+P351+P338
Class:
-
Packing Group:
-

NMR Spectrum

Other Analytical Data

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Chemical Structure


The unique compound, ((4-Bromophenyl)ethynyl)trimethylsilane, plays a critical role in chemical synthesis as a versatile building block for various organic reactions. This specialized reagent is widely utilized in the synthesis of complex organic molecules due to its ability to introduce the 4-bromophenyl and ethynyl functional groups into a wide range of substrates. One of the key applications of ((4-Bromophenyl)ethynyl)trimethylsilane is in cross-coupling reactions, where it serves as a valuable source of the aryl acetylene moiety. This compound can undergo efficient Sonogashira coupling reactions with suitable partners under mild conditions to construct carbon-carbon bonds. Additionally, the trimethylsilyl group enhances the compatibility and reactivity of the molecule in diverse synthetic transformations.Furthermore, ((4-Bromophenyl)ethynyl)trimethylsilane can participate in nucleophilic substitution reactions, enabling the selective functionalization of aromatic systems. Its presence can facilitate the introduction of the ethynyl group into aryl halides, leading to the synthesis of alkynes with tailored substitution patterns.Overall, the strategic incorporation of ((4-Bromophenyl)ethynyl)trimethylsilane in chemical synthesis allows for the efficient construction of complex organic structures and the synthesis of valuable intermediates for drug discovery, materials science, and other applications.