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Brc1cnc(nc1)C
Pyrimidine, 5-bromo-2-methyl-
CCCP1(=O)OP(=O)(CCC)OP(=O)(O1)CCC
1,3,5,2,4,6-Trioxatriphosphorinane, 2,4,6-tripropyl-, 2,4,6-trioxide
CC1(C)OB(OC1(C)C)B1OC(C(O1)(C)C)(C)C
2,2'-Bi-1,3,2-dioxaborolane, 4,4,4',4',5,5,5',5'-octamethyl-
O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.[Pd].[Pd]
Tris(dibenzylideneacetone)dipalladium
C1CCC(CC1)P(C1CCCCC1)C1CCCCC1.Cc1cc(C)c(c(c1)C)N1CCN(C1=[Ru](=Cc1ccccc1)(Cl)Cl)c1c(C)cc(cc1C)C
Ruthenium,[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)-, (SP-5-41)-

4-chloro-8-fluoro-2-(trifluoromethyl)quinazoline

Fc1cccc2c1nc(nc2Cl)C(F)(F)F Request for Quotation
Chemical Name: 4-chloro-8-fluoro-2-(trifluoromethyl)quinazoline
CAS Number: 959238-18-7
Product Number: AG005WHF(AGN-PC-0NP8M4)
Synonyms:
MDL No:
Molecular Formula: C9H3ClF4N2
Molecular Weight: 250.5801

Identification/Properties

Properties
BP:
175.6±40.0°C at 760 mmHg
Storage:
Inert atmosphere;2-8℃;
Computed Properties
Molecular Weight:
250.581g/mol
XLogP3:
3.5
Hydrogen Bond Donor Count:
0
Hydrogen Bond Acceptor Count:
6
Rotatable Bond Count:
0
Exact Mass:
249.992g/mol
Monoisotopic Mass:
249.992g/mol
Topological Polar Surface Area:
25.8A^2
Heavy Atom Count:
16
Formal Charge:
0
Complexity:
260
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
0
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information

GHS Pictogram:
Signal Word:
Warning
UN#:
N/A
Hazard Statements:
H315-H319-H335
Precautionary Statements:
P261-P305+P351+P338
Class:
N/A
Packing Group:
N/A

NMR Spectrum

Other Analytical Data

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Chemical Structure


4-Chloro-8-fluoro-2-(trifluoromethyl)quinazoline is a versatile compound widely utilized in chemical synthesis for its unique properties and reactivity. One significant application of this compound is its role as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its strategic position within the quinazoline framework allows for selective functionalization, enabling the introduction of diverse functional groups at specific positions.Furthermore, 4-Chloro-8-fluoro-2-(trifluoromethyl)quinazoline serves as a valuable building block for the preparation of novel heterocyclic compounds with potential biological activity. The presence of the chloro, fluoro, and trifluoromethyl substituents imparts specific physicochemical properties to the resulting molecules, making them attractive candidates for drug discovery programs.In addition to its pharmaceutical applications, this compound also finds utility in material science and advanced organic synthesis. Its versatile reactivity and compatibility with various reaction conditions make it a valuable tool for the construction of complex molecular architectures. By harnessing the unique properties of 4-Chloro-8-fluoro-2-(trifluoromethyl)quinazoline, chemists can access a diverse array of functionalized compounds with potential applications across multiple industries.