Chemical Name: | D-Cysteine, S-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]- |
CAS Number: | 131766-22-8 |
Product Number: | AG000ZPG(AGN-PC-0O10O3) |
Synonyms: | |
MDL No: | |
Molecular Formula: | C22H25NO4S |
Molecular Weight: | 399.5032 |
Fmoc-D-Cys(tBu)-OH is a key reagent widely utilized in chemical synthesis processes, particularly in the field of peptide synthesis. This compound, which consists of a protected cysteine amino acid residue attached to a Fmoc protecting group, plays a crucial role in the preparation of custom peptides with specific sequences and functionalities.One of the primary applications of Fmoc-D-Cys(tBu)-OH is in solid-phase peptide synthesis, where it serves as a building block for incorporating cysteine residues into linear peptide chains. The Fmoc protecting group enables selective deprotection and subsequent coupling reactions, allowing for controlled assembly of peptide sequences with high purity and efficiency.Furthermore, the tert-butyl (tBu) protecting group on the cysteine thiol group provides enhanced stability during peptide synthesis, preventing undesired side reactions and promoting the desired peptide bond formation. This protection strategy is particularly valuable in the presence of sensitive functional groups or in complex peptide sequences where precise reactivity control is essential.Overall, Fmoc-D-Cys(tBu)-OH is a versatile reagent that enables chemists to efficiently and effectively incorporate cysteine residues into peptides, facilitating the synthesis of diverse peptide-based molecules for research, pharmaceutical development, and other applications in the field of organic chemistry.