Adenosine, 8-azido-


Chemical Name: Adenosine, 8-azido-
CAS Number: 4372-67-2
Product Number: AG00D9Y6(AGN-PC-0OAF7Y)
Synonyms:
MDL No:
Molecular Formula: C10H12N8O4
Molecular Weight: 308.25348

Identification/Properties


Properties
MP:
>164°C (dec.)
Storage:
2-8℃;Inert atmosphere;
Form:
Solid
Computed Properties
Molecular Weight:
308.258g/mol
XLogP3:
0.2
Hydrogen Bond Donor Count:
4
Hydrogen Bond Acceptor Count:
10
Rotatable Bond Count:
3
Exact Mass:
308.098g/mol
Monoisotopic Mass:
308.098g/mol
Topological Polar Surface Area:
154A^2
Heavy Atom Count:
22
Formal Charge:
0
Complexity:
462
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
4
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
1
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information


NMR Spectrum


Other Analytical Data


Request for Quotation


Customer Feedback


Chemical Structure



8-Azidoadenosine, a versatile nucleoside analogue, finds extensive application in chemical synthesis as a powerful building block for the modification and functionalization of various biomolecules. This compound serves as a strategic precursor in bioconjugation reactions due to its unique azide functionality, which can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions with alkynes or other organic azides.In chemical synthesis, 8-Azidoadenosine is used for the site-specific labeling of biomolecules such as proteins, nucleic acids, and carbohydrates. By introducing the azido group at specific locations within the target molecule, researchers can subsequently attach a wide range of diverse compounds or tags under mild conditions without affecting the overall structure or function of the biomolecule.Moreover, the ability of 8-Azidoadenosine to participate in bio-orthogonal reactions makes it a valuable tool for studying biological processes in complex systems. Through selective functionalization using click chemistry, researchers can track and visualize the behavior of biomolecules in living systems, aiding in drug discovery, diagnostics, and molecular imaging applications.Overall, the unique properties of 8-Azidoadenosine make it an indispensable reagent in modern chemical synthesis techniques, enabling precise and selective modifications of biomolecules for a wide range of scientific and biomedical applications.