Chemical Name: | 1H-Indazole, 3-(trifluoromethyl)- |
CAS Number: | 57631-05-7 |
Product Number: | AG00EL9L(AGN-PC-0OCLK0) |
Synonyms: | |
MDL No: | |
Molecular Formula: | C8H5F3N2 |
Molecular Weight: | 186.1339 |
3-(Trifluoromethyl)-1H-indazole is a unique and versatile building block in chemical synthesis, particularly in the field of pharmaceuticals and agrochemicals. Its trifluoromethyl group imparts valuable properties such as increased lipophilicity, metabolic stability, and bioavailability to the compounds derived from it. This makes 3-(Trifluoromethyl)-1H-indazole an important moiety for drug design and discovery processes.In modern chemical synthesis, this compound can be used as a key intermediate in the preparation of various pharmaceutical agents, including but not limited to anti-inflammatory drugs, antiviral agents, and enzyme inhibitors. Its structural characteristics make it a valuable tool for modifying the potency and pharmacokinetic profiles of drug candidates, leading to the development of more effective and safer medications.Furthermore, 3-(Trifluoromethyl)-1H-indazole's compatibility with a wide range of synthetic methodologies allows for the introduction of diverse functional groups at specific positions on the molecule, enabling fine-tuning of the desired biological activity. Its versatility and synthetic accessibility make it a valuable asset in medicinal chemistry research and the development of novel therapeutics with improved efficacy and pharmacological properties.