Ethanone, 1-[(3R)-3-hydroxy-1-pyrrolidinyl]-


Chemical Name: Ethanone, 1-[(3R)-3-hydroxy-1-pyrrolidinyl]-
CAS Number: 916733-17-0
Product Number: AG003C7U(AGN-PC-0OMUSU)
Synonyms:
MDL No: MFCD09909313
Molecular Formula: C6H11NO2
Molecular Weight: 129.1570

Identification/Properties


Properties
MP:
83 °C
BP:
286.4°C at 760 mmHg
Storage:
Keep in dry area;Room Temperature;
Form:
Solid
Refractive Index:
-42 ° (C=3, MeOH)
Computed Properties
Molecular Weight:
129.159g/mol
XLogP3:
-0.8
Hydrogen Bond Donor Count:
1
Hydrogen Bond Acceptor Count:
2
Rotatable Bond Count:
0
Exact Mass:
129.079g/mol
Monoisotopic Mass:
129.079g/mol
Topological Polar Surface Area:
40.5A^2
Heavy Atom Count:
9
Formal Charge:
0
Complexity:
124
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
1
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

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NMR Spectrum


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Chemical Structure



(R)-1-Acetyl-3-hydroxypyrrolidine, also known as (R)-A3HP, is a valuable chiral building block in chemical synthesis. This compound plays a crucial role in asymmetric synthesis, as its unique structure provides stereochemical control in various chemical reactions. In organic chemistry, (R)-1-acetyl-3-hydroxypyrrolidine is widely utilized as a key intermediate for the preparation of enantiomerically pure compounds. Its chiral nature allows for the synthesis of complex molecules with high optical purity, making it a versatile tool in the pharmaceutical and agrochemical industries. One notable application of (R)-A3HP is in the synthesis of bioactive molecules, where precise control over stereochemistry is essential for achieving the desired biological activity. By incorporating (R)-1-acetyl-3-hydroxypyrrolidine into the synthesis route, chemists can efficiently access enantiomerically enriched compounds with potential therapeutic benefits.Overall, the use of (R)-1-acetyl-3-hydroxypyrrolidine in chemical synthesis enables chemists to engage in asymmetric transformations and stereoselective reactions, paving the way for the creation of structurally diverse and stereochemically enriched compounds for various applications.