Chemical Name: | D-Histidine, N-[(1,1-dimethylethoxy)carbonyl]-3-[(phenylmethoxy)methyl]- |
CAS Number: | 99310-01-7 |
Product Number: | AG003OGJ(AGN-PC-0OP3YQ) |
Synonyms: | |
MDL No: | |
Molecular Formula: | C19H25N3O5 |
Molecular Weight: | 375.4189 |
Boc-D-His(Bom)-OH, also known as N-tert-butoxycarbonyl-D-histidine (Bom)-OH, is a key compound used in chemical synthesis with its unique properties and applications. This amino acid derivative is commonly utilized as a building block in peptide synthesis and pharmaceutical research. Due to its Boc (tert-butoxycarbonyl) protecting group on the amino group and the Bom (benzyloxymethyl) protecting group on the imidazole nitrogen, Boc-D-His(Bom)-OH offers excellent stability during various chemical reactions.In peptide synthesis, Boc-D-His(Bom)-OH serves as a crucial component for constructing histidine-containing peptides or proteins. The Boc protecting group ensures the selective deprotection of the amino group in a controlled manner, while the Bom protecting group safeguards the imidazole nitrogen from unwanted side reactions. This enables chemists to manipulate the sequence and structure of peptides with high precision and efficiency.Furthermore, Boc-D-His(Bom)-OH finds applications in the synthesis of pharmaceuticals, where the incorporation of histidine residues is important for enhancing biological activity or targeting specific biological pathways. By using Boc-D-His(Bom)-OH as a building block in drug development, researchers can design and create novel peptide-based drugs with improved therapeutic properties and reduced side effects.Overall, the versatile nature of Boc-D-His(Bom)-OH makes it a valuable tool in chemical synthesis, particularly in peptide chemistry and drug discovery, where precise control over amino acid sequences and functionalities is essential for achieving desired biochemical and pharmacological outcomes.