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Brc1cnc(nc1)C
Pyrimidine, 5-bromo-2-methyl-
CCCP1(=O)OP(=O)(CCC)OP(=O)(O1)CCC
1,3,5,2,4,6-Trioxatriphosphorinane, 2,4,6-tripropyl-, 2,4,6-trioxide
CC1(C)OB(OC1(C)C)B1OC(C(O1)(C)C)(C)C
2,2'-Bi-1,3,2-dioxaborolane, 4,4,4',4',5,5,5',5'-octamethyl-
O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.[Pd].[Pd]
Tris(dibenzylideneacetone)dipalladium
C1CCC(CC1)P(C1CCCCC1)C1CCCCC1.Cc1cc(C)c(c(c1)C)N1CCN(C1=[Ru](=Cc1ccccc1)(Cl)Cl)c1c(C)cc(cc1C)C
Ruthenium,[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)-, (SP-5-41)-

9H-Purin-6-amine, 2-chloro-9-(2-deoxy-2-fluoro-b-D-arabinofuranosyl)-

OC[C@H]1O[C@H]([C@H]([C@@H]1O)F)n1cnc2c1nc(Cl)nc2N Request for Quotation
Chemical Name: 9H-Purin-6-amine, 2-chloro-9-(2-deoxy-2-fluoro-b-D-arabinofuranosyl)-
CAS Number: 123318-82-1
Product Number: AG000KCJ(AGN-PC-0PHCIM)
Synonyms:
MDL No: MFCD00871077
Molecular Formula: C10H11ClFN5O3
Molecular Weight: 303.6774

Identification/Properties

Computed Properties
Molecular Weight:
303.678g/mol
XLogP3:
0.9
Hydrogen Bond Donor Count:
3
Hydrogen Bond Acceptor Count:
8
Rotatable Bond Count:
2
Exact Mass:
303.053g/mol
Monoisotopic Mass:
303.053g/mol
Topological Polar Surface Area:
119A^2
Heavy Atom Count:
20
Formal Charge:
0
Complexity:
370
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
4
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information

GHS Pictogram:
Signal Word:
Danger
UN#:
2811
Hazard Statements:
H300
Precautionary Statements:
P264-P301+P310
Class:
6.1
Packing Group:
Ⅲ

NMR Spectrum

Other Analytical Data

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Chemical Structure


2-Chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purin-6-amine, commonly referred to as $name$, is a key compound utilized in chemical synthesis for its versatile applications. In the realm of organic chemistry, $name$ plays a crucial role as a building block for the synthesis of nucleoside analogs. Its unique structure, which combines a purine base with a fluorinated deoxyribose sugar moiety, offers researchers a valuable tool for the development of novel pharmaceuticals and nucleoside-based therapeutics. The presence of the chloro group further enhances its reactivity, allowing for selective modifications and functionalizations during synthetic processes.$name$ is particularly valuable in the field of medicinal chemistry, where it can be utilized to design new antiviral or anticancer agents. By strategically incorporating this compound into molecular structures, chemists can tailor the properties of the resulting molecules to exhibit desirable pharmacological profiles, such as enhanced potency, improved bioavailability, or decreased toxicity.Moreover, in the synthesis of nucleoside analogs, $name$ serves as a precursor for the introduction of fluorinated sugars, a modification known to impart beneficial properties to nucleoside compounds, including altered metabolic stability and resistance to enzymatic degradation. This feature makes $name$ a valuable tool for researchers aiming to develop nucleoside analogs with improved therapeutic potential and pharmacokinetic properties.Overall, the application of 2-Chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purin-6-amine in chemical synthesis showcases its significance in advancing drug discovery efforts and expanding the molecular diversity of bioactive compounds.