Benzenepropanamine, g-[4-(trifluoromethyl)phenoxy]-, (gR)-


Chemical Name: Benzenepropanamine, g-[4-(trifluoromethyl)phenoxy]-, (gR)-
CAS Number: 130194-43-3
Product Number: AG000U3Q(AGN-PC-0PJ5W4)
Synonyms:
MDL No:
Molecular Formula: C16H16F3NO
Molecular Weight: 295.2995

Identification/Properties


Computed Properties
Molecular Weight:
295.305g/mol
XLogP3:
3.5
Hydrogen Bond Donor Count:
1
Hydrogen Bond Acceptor Count:
5
Rotatable Bond Count:
5
Exact Mass:
295.118g/mol
Monoisotopic Mass:
295.118g/mol
Topological Polar Surface Area:
35.2A^2
Heavy Atom Count:
21
Formal Charge:
0
Complexity:
294
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
1
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

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NMR Spectrum


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Chemical Structure



The chiral compound (R)-Norfluoxetine, also known as (R)-N-Methyl-3-phenyl-3-(α,α,α-trifluoro-p-tolyl)propylamine, finds wide application in chemical synthesis as a valuable building block. Its unique stereochemistry and functional groups make it a versatile intermediate in the preparation of various pharmaceuticals and agrochemicals. (R)-Norfluoxetine can be employed in the synthesis of diverse molecules such as selective serotonin reuptake inhibitors (SSRIs), which are commonly used in the treatment of depression and anxiety disorders. Additionally, its trifluoromethyl group imparts special properties to the molecules it is incorporated into, enhancing their biological activities and metabolic stability. The utilization of (R)-Norfluoxetine in chemical synthesis showcases its significance in the development of novel compounds with potential therapeutic applications.