b-D-Ribofuranuronamide,1-(6-amino-2-iodo-9H-purin-9-yl)-1-deoxy-N-ethyl-


Chemical Name: b-D-Ribofuranuronamide,1-(6-amino-2-iodo-9H-purin-9-yl)-1-deoxy-N-ethyl-
CAS Number: 141018-29-3
Product Number: AG001FQZ(AGN-PC-0PQ57W)
Synonyms:
MDL No:
Molecular Formula: C12H15IN6O4
Molecular Weight: 434.1898

Identification/Properties


Computed Properties
Molecular Weight:
434.194g/mol
XLogP3:
-0.9
Hydrogen Bond Donor Count:
4
Hydrogen Bond Acceptor Count:
8
Rotatable Bond Count:
3
Exact Mass:
434.02g/mol
Monoisotopic Mass:
434.02g/mol
Topological Polar Surface Area:
148A^2
Heavy Atom Count:
23
Formal Charge:
0
Complexity:
459
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
3
Undefined Atom Stereocenter Count:
1
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

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NMR Spectrum


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Chemical Structure



2-Iodo-5'-ethylcarboxamido Adenosine, commonly referred to as 2-IECA, is a valuable chemical compound widely utilized in the field of chemical synthesis. This compound is particularly notable for its application in nucleotide chemistry, where it serves as a critical building block for the synthesis of nucleoside analogs.By incorporating 2-IECA into molecular structures, chemists are able to introduce specific functional groups and modifications that can enhance the biological activity or stability of nucleotide-based compounds. These modifications can be crucial for the development of pharmaceuticals, as they can improve drug efficacy, bioavailability, and selective targeting of cellular processes.In addition, 2-IECA is often used in the creation of nucleoside triphosphates, which are essential precursors for DNA and RNA synthesis in both biochemical research and pharmaceutical development. The versatility of 2-IECA in chemical synthesis makes it a valuable tool for the design and creation of novel nucleotide analogs with tailored properties for various applications in biotechnology, medicinal chemistry, and drug discovery.