1. Home
  2. 2-Pyrrolidinecarboxamide,1-[[(2R,3S)-5-chloro-3-(2-chlorophenyl)-1-[(3,4-dimethoxyphenyl)sulfonyl]-2,3-dihydro-3-hydroxy-1H-indol-2-yl]carbonyl]-, (2S)-

Contact Angene

Tel: +852 8191 6999

Email: [email protected]

Brc1cnc(nc1)C
Pyrimidine, 5-bromo-2-methyl-
CCCP1(=O)OP(=O)(CCC)OP(=O)(O1)CCC
1,3,5,2,4,6-Trioxatriphosphorinane, 2,4,6-tripropyl-, 2,4,6-trioxide
CC1(C)OB(OC1(C)C)B1OC(C(O1)(C)C)(C)C
2,2'-Bi-1,3,2-dioxaborolane, 4,4,4',4',5,5,5',5'-octamethyl-
O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.O=C(C=Cc1ccccc1)C=Cc1ccccc1.[Pd].[Pd]
Tris(dibenzylideneacetone)dipalladium
C1CCC(CC1)P(C1CCCCC1)C1CCCCC1.Cc1cc(C)c(c(c1)C)N1CCN(C1=[Ru](=Cc1ccccc1)(Cl)Cl)c1c(C)cc(cc1C)C
Ruthenium,[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro(phenylmethylene)(tricyclohexylphosphine)-, (SP-5-41)-

2-Pyrrolidinecarboxamide,1-[[(2R,3S)-5-chloro-3-(2-chlorophenyl)-1-[(3,4-dimethoxyphenyl)sulfonyl]-2,3-dihydro-3-hydroxy-1H-indol-2-yl]carbonyl]-, (2S)-

COc1ccc(cc1OC)S(=O)(=O)N1c2ccc(cc2[C@]([C@@H]1C(=O)N1CCC[C@H]1C(=O)N)(O)c1ccccc1Cl)Cl Request for Quotation
Chemical Name: 2-Pyrrolidinecarboxamide,1-[[(2R,3S)-5-chloro-3-(2-chlorophenyl)-1-[(3,4-dimethoxyphenyl)sulfonyl]-2,3-dihydro-3-hydroxy-1H-indol-2-yl]carbonyl]-, (2S)-
CAS Number: 150375-75-0
Product Number: AG001MJV(AGN-PC-0Q4N4V)
Synonyms:
MDL No: MFCD00922133
Molecular Formula: C28H27Cl2N3O7S
Molecular Weight: 620.5009

Identification/Properties

Computed Properties
Molecular Weight:
620.498g/mol
XLogP3:
3.8
Hydrogen Bond Donor Count:
2
Hydrogen Bond Acceptor Count:
8
Rotatable Bond Count:
7
Exact Mass:
619.095g/mol
Monoisotopic Mass:
619.095g/mol
Topological Polar Surface Area:
148A^2
Heavy Atom Count:
41
Formal Charge:
0
Complexity:
1090
Isotope Atom Count:
0
Defined Atom Stereocenter Count:
3
Undefined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Covalently-Bonded Unit Count:
1
Compound Is Canonicalized:
Yes

Safety Information

NMR Spectrum

Other Analytical Data

Request for Quotation

Customer Feedback

Chemical Structure


Sr49059, also known as sorivudine, is a potent and selective antagonist of the neurokinin-1 receptor. This receptor plays a crucial role in various physiological processes, including the transmission of pain signals, regulation of mood, and control of inflammatory responses. In chemical synthesis, Sr49059 is utilized as a valuable tool for studying neurokinin-1 receptor functions and developing novel therapeutic agents targeting this receptor.One of the key applications of Sr49059 in chemical synthesis is its use in the design and optimization of neurokinin-1 receptor antagonists. By understanding the structure-activity relationship of Sr49059 and related compounds, researchers can modify the chemical properties to improve selectivity, potency, and pharmacokinetic profile. These efforts are crucial for developing more effective drugs for the treatment of pain, mood disorders, and inflammation.Moreover, Sr49059 serves as a useful pharmacological probe for investigating the role of the neurokinin-1 receptor in various disease states. By blocking the receptor activity selectively with Sr49059, researchers can elucidate the biological mechanisms underlying pain perception, stress responses, and immune modulation. This knowledge can lead to the identification of new drug targets and the development of innovative therapeutic strategies.In summary, Sr49059 is a valuable compound in chemical synthesis, particularly for studying the neurokinin-1 receptor and its impact on physiological processes. Its applications extend to drug discovery, pharmacological research, and understanding the complex interplay between neurokinin signaling and disease pathology.